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stemvision colony marker  (STEMCELL Technologies Inc)

 
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    Structured Review

    STEMCELL Technologies Inc stemvision colony marker
    IDH1 -R132H and IDH2 -R140Q mutations drive a block of CFU ability in human CD34+ HSPC, which is released by specific inhibitors. The CFU assay of transduced hCD34+ cells with an empty vector, IDH1 wild-type, or IDH1 -R132H (n = 7), ±AG-120 inhibitor (n = 3 of 7) ( A ); empty vector, IDH2 wild-type, or IDH2 -R140 (n = 6), ±AG-221 inhibitor (n = 4 of 6) ( B ). Graphs on the left represent the percentage of total colonies that rose after 14 days. Panels on the right are representative images of wells (top row) and types of colonies (bottom row) obtained using the <t>STEMvision™.</t> Colony marker application: red circles identify BFU-E-derived colonies; yellow circles identify CFU-G/M/GM-derived colonies; blue circles identify CFU-GEMM-derived colonies; and orange circles identify CFU-E-derived colonies (one-way ANOVA analyses **** p < 0.0001, *** p < 0.001, ** p < 0.01, * p < 0.05).
    Stemvision Colony Marker, supplied by STEMCELL Technologies Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/stemvision colony marker/product/STEMCELL Technologies Inc
    Average 90 stars, based on 1 article reviews
    stemvision colony marker - by Bioz Stars, 2026-05
    90/100 stars

    Images

    1) Product Images from "The Leukemic Isocitrate Dehydrogenase (IDH) 1/2 Mutations Impair Myeloid and Erythroid Cell Differentiation of Primary Human Hematopoietic Stem and Progenitor Cells (HSPCs)"

    Article Title: The Leukemic Isocitrate Dehydrogenase (IDH) 1/2 Mutations Impair Myeloid and Erythroid Cell Differentiation of Primary Human Hematopoietic Stem and Progenitor Cells (HSPCs)

    Journal: Cancers

    doi: 10.3390/cancers16152675

    IDH1 -R132H and IDH2 -R140Q mutations drive a block of CFU ability in human CD34+ HSPC, which is released by specific inhibitors. The CFU assay of transduced hCD34+ cells with an empty vector, IDH1 wild-type, or IDH1 -R132H (n = 7), ±AG-120 inhibitor (n = 3 of 7) ( A ); empty vector, IDH2 wild-type, or IDH2 -R140 (n = 6), ±AG-221 inhibitor (n = 4 of 6) ( B ). Graphs on the left represent the percentage of total colonies that rose after 14 days. Panels on the right are representative images of wells (top row) and types of colonies (bottom row) obtained using the STEMvision™. Colony marker application: red circles identify BFU-E-derived colonies; yellow circles identify CFU-G/M/GM-derived colonies; blue circles identify CFU-GEMM-derived colonies; and orange circles identify CFU-E-derived colonies (one-way ANOVA analyses **** p < 0.0001, *** p < 0.001, ** p < 0.01, * p < 0.05).
    Figure Legend Snippet: IDH1 -R132H and IDH2 -R140Q mutations drive a block of CFU ability in human CD34+ HSPC, which is released by specific inhibitors. The CFU assay of transduced hCD34+ cells with an empty vector, IDH1 wild-type, or IDH1 -R132H (n = 7), ±AG-120 inhibitor (n = 3 of 7) ( A ); empty vector, IDH2 wild-type, or IDH2 -R140 (n = 6), ±AG-221 inhibitor (n = 4 of 6) ( B ). Graphs on the left represent the percentage of total colonies that rose after 14 days. Panels on the right are representative images of wells (top row) and types of colonies (bottom row) obtained using the STEMvision™. Colony marker application: red circles identify BFU-E-derived colonies; yellow circles identify CFU-G/M/GM-derived colonies; blue circles identify CFU-GEMM-derived colonies; and orange circles identify CFU-E-derived colonies (one-way ANOVA analyses **** p < 0.0001, *** p < 0.001, ** p < 0.01, * p < 0.05).

    Techniques Used: Blocking Assay, Colony-forming Unit Assay, Plasmid Preparation, Marker, Derivative Assay



    Similar Products

    stemvision colony marker  (STEMCELL Technologies Inc)
    90
    STEMCELL Technologies Inc stemvision colony marker
    IDH1 -R132H and IDH2 -R140Q mutations drive a block of CFU ability in human CD34+ HSPC, which is released by specific inhibitors. The CFU assay of transduced hCD34+ cells with an empty vector, IDH1 wild-type, or IDH1 -R132H (n = 7), ±AG-120 inhibitor (n = 3 of 7) ( A ); empty vector, IDH2 wild-type, or IDH2 -R140 (n = 6), ±AG-221 inhibitor (n = 4 of 6) ( B ). Graphs on the left represent the percentage of total colonies that rose after 14 days. Panels on the right are representative images of wells (top row) and types of colonies (bottom row) obtained using the <t>STEMvision™.</t> Colony marker application: red circles identify BFU-E-derived colonies; yellow circles identify CFU-G/M/GM-derived colonies; blue circles identify CFU-GEMM-derived colonies; and orange circles identify CFU-E-derived colonies (one-way ANOVA analyses **** p < 0.0001, *** p < 0.001, ** p < 0.01, * p < 0.05).
    Stemvision Colony Marker, supplied by STEMCELL Technologies Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/stemvision colony marker/product/STEMCELL Technologies Inc
    Average 90 stars, based on 1 article reviews
    stemvision colony marker - by Bioz Stars, 2026-05
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    IDH1 -R132H and IDH2 -R140Q mutations drive a block of CFU ability in human CD34+ HSPC, which is released by specific inhibitors. The CFU assay of transduced hCD34+ cells with an empty vector, IDH1 wild-type, or IDH1 -R132H (n = 7), ±AG-120 inhibitor (n = 3 of 7) ( A ); empty vector, IDH2 wild-type, or IDH2 -R140 (n = 6), ±AG-221 inhibitor (n = 4 of 6) ( B ). Graphs on the left represent the percentage of total colonies that rose after 14 days. Panels on the right are representative images of wells (top row) and types of colonies (bottom row) obtained using the STEMvision™. Colony marker application: red circles identify BFU-E-derived colonies; yellow circles identify CFU-G/M/GM-derived colonies; blue circles identify CFU-GEMM-derived colonies; and orange circles identify CFU-E-derived colonies (one-way ANOVA analyses **** p < 0.0001, *** p < 0.001, ** p < 0.01, * p < 0.05).

    Journal: Cancers

    Article Title: The Leukemic Isocitrate Dehydrogenase (IDH) 1/2 Mutations Impair Myeloid and Erythroid Cell Differentiation of Primary Human Hematopoietic Stem and Progenitor Cells (HSPCs)

    doi: 10.3390/cancers16152675

    Figure Lengend Snippet: IDH1 -R132H and IDH2 -R140Q mutations drive a block of CFU ability in human CD34+ HSPC, which is released by specific inhibitors. The CFU assay of transduced hCD34+ cells with an empty vector, IDH1 wild-type, or IDH1 -R132H (n = 7), ±AG-120 inhibitor (n = 3 of 7) ( A ); empty vector, IDH2 wild-type, or IDH2 -R140 (n = 6), ±AG-221 inhibitor (n = 4 of 6) ( B ). Graphs on the left represent the percentage of total colonies that rose after 14 days. Panels on the right are representative images of wells (top row) and types of colonies (bottom row) obtained using the STEMvision™. Colony marker application: red circles identify BFU-E-derived colonies; yellow circles identify CFU-G/M/GM-derived colonies; blue circles identify CFU-GEMM-derived colonies; and orange circles identify CFU-E-derived colonies (one-way ANOVA analyses **** p < 0.0001, *** p < 0.001, ** p < 0.01, * p < 0.05).

    Article Snippet: Colonies were counted and characterized by subtype after 14 days of culture using the STEMvision™ instrument and its analysis software STEMvision Colony Marker ( https://www.stemcell.com/products/brands/stemvision-automated-imaging-colony-assay.html , accessed on 24 July 2024; STEMCELL™ Tech, Vancouver, BC, Canada).

    Techniques: Blocking Assay, Colony-forming Unit Assay, Plasmid Preparation, Marker, Derivative Assay